Milan have suspended Franck Kessie and Tiemoue Bakayoko and three other players for Saturday’s games against Fiorentina.
The Disciplinary Commission released its verdicts after the Week 16 fixtures were completed last night.
Bakayoko was sent off against Bologna, resulting in an immediate one-match ban, while Kessie received his fifth yellow card of the campaign.
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It means Milan will be missing their entire first choice midfield in the showdown for European ambitions.
Also suspended this week in Serie A are Kwadwo Asamoah (Inter), Rade Krunic (Empoli) and Ivan Radovanovic (Chievo).
Lazio were fined €4,000 for starting their game five minutes late.
Milan and Roma were both fined €3,000 after supporters threw fireworks.